TC‐5214 (S‐(+)‐Mecamylamine): A Neuronal Nicotinic Receptor Modulator with Antidepressant Activity

Both clinical and preclinical data support a potential therapeutic benefit of modulating the activity of CNS neuronal nicotinic receptors (NNRs) to treat depression and anxiety disorders. Based on the notion that the depressive states involve hypercholinergic tone, we have examined the potential pal...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Lippiello, Patrick M., Beaver, Jessica S., Gatto, Gregory J., James, John W., Jordan, Kristen G., Traina, Vincent M., Xie, Jianxun, Bencherif, Merouane
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Drug Focus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494058/
https://ncbi.nlm.nih.gov/pubmed/19040552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-5949.2008.00054.x
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