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All Roads to Schizophrenia Lead to Dopamine Supersensitivity and Elevated Dopamine D2(High) Receptors
Background: The dopamine D2 receptor is the common target for antipsychotics, and the antipsychotic clinical doses correlate with their affinities for this receptor. Antipsychotics quickly enter the brain to occupy 60–80% of brain D2 receptors in patients (the agonist aripiprazole occupies up to 90%...
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| Veröffentlicht in: | CNS Neurosci Ther |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Ltd
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6493870/ https://ncbi.nlm.nih.gov/pubmed/20560996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-5949.2010.00162.x |
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