Inhibition of Tityus serrulatus venom hyaluronidase affects venom biodistribution

BACKGROUND: The hyaluronidase enzyme is generally known as a spreading factor in animal venoms. Although its activity has been demonstrated in several organisms, a deeper knowledge about hyaluronidase and the venom spreading process from the bite/sting site until its elimination from the victim'...

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Udgivet i:PLoS Negl Trop Dis
Main Authors: de Oliveira-Mendes, Bárbara Bruna Ribeiro, Miranda, Sued Eustáquio Mendes, Sales-Medina, Douglas Ferreira, Magalhães, Bárbara de Freitas, Kalapothakis, Yan, de Souza, Renan Pedra, Cardoso, Valbert Nascimento, de Barros, André Luís Branco, Guerra-Duarte, Clara, Kalapothakis, Evanguedes, Horta, Carolina Campolina Rebello
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
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Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493768/
https://ncbi.nlm.nih.gov/pubmed/31002673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007048
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