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Fluoxetine Induces Hepatic Lipid Accumulation Via Both Promotion of the SREBP1c‐Related Lipogenesis and Reduction of Lipolysis in Primary Mouse Hepatocytes
AIMS: In this study, we investigated the peripheral mechanisms underlying the metabolic side effects of fluoxetine (FLX) by focusing on hepatic lipid metabolism. METHODS: Primary mouse hepatocytes were prepared from male mice by the two‐step perfusion method. The lipid accumulation in primary mouse...
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| Publicado no: | CNS Neurosci Ther |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6493645/ https://ncbi.nlm.nih.gov/pubmed/23137031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12014 |
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