Simvastatin Induces Neuroprotection in 6‐OHDA‐Lesioned PC12 via the PI3K/AKT/Caspase 3 Pathway and Anti‐Inflammatory Responses

BACKGROUND: In addition to their original applications for lowering cholesterol, statins display multiple neuroprotective effects. Inflammatory reactions and the PI3K/AKT/caspase 3 pathway are strongly implicated in dopaminergic neuronal death in Parkinson's disease (PD). This study aims to inv...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Xu, Yun‐Qi, Long, Ling, Yan, Jun‐Qiang, Wei, Lei, Pan, Meng‐Qiu, Gao, Hui‐Min, Zhou, Peng, Liu, Mei, Zhu, Can‐Sheng, Tang, Bei‐Sha, Wang, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493537/
https://ncbi.nlm.nih.gov/pubmed/23279934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12053
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