Sigma‐1 Receptor Knockout Impairs Neurogenesis in Dentate Gyrus of Adult Hippocampus Via Down‐Regulation of NMDA Receptors

AIMS: This study investigated the influence of sigma‐1 receptor (σ(1) R) deficiency on adult neurogenesis. METHODS: We employed 8‐week‐old male σ(1) R knockout (σ(1) R (−/−)) mice to examine the proliferation and differentiation of progenitor cells, and the survival and neurite growth of newborn neu...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Sha, Sha, Qu, Wei‐Jun, Li, Lin, Lu, Zi‐Hong, Chen, Lei, Yu, Wen‐Feng, Chen, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493366/
https://ncbi.nlm.nih.gov/pubmed/23745740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12129
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