Phase 2, randomized, open-label study on catheter-directed thrombolysis with plasmin versus rtPA and placebo in acute peripheral arterial occlusion

Background: Patients with acute peripheral arterial occlusion (aPAO) are candidates for operative thrombectomy, bypass, or catheter-directed thrombolysis (CDT) using a plasminogen activator. Human plasma-derived plasmin may offer another CDT option. Objectives: To evaluate the efficacy, safety, and...

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Bibliographic Details
Published in:J Drug Assess
Main Authors: Comerota, Anthony J., Davidovic, Lazar, Hanna, Kim, Courtney, Kecia L., Shlansky-Goldberg, Richard D.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2019
Subjects:
Cardiovascular Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493290/
https://ncbi.nlm.nih.gov/pubmed/31069128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21556660.2019.1586402
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