Lenti‐GDNF Gene Therapy Protects Against Alzheimer's Disease‐Like Neuropathology in 3xTg‐AD Mice and MC65 Cells

AIMS: Glial cell‐derived neurotrophic factor (GDNF) is emerging as a potent neurotrophic factor with therapeutic potential against a range of neurodegenerative conditions including Alzheimer's disease (AD). We assayed the effects of GDNF treatment in AD experimental models through gene‐therapy...

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Veröffentlicht in:CNS Neurosci Ther
Hauptverfasser: Revilla, Susana, Ursulet, Suzanna, Álvarez‐López, María Jesús, Castro‐Freire, Marco, Perpiñá, Unai, García‐Mesa, Yoelvis, Bortolozzi, Analía, Giménez‐Llort, Lydia, Kaliman, Perla, Cristòfol, Rosa, Sarkis, Chamsy, Sanfeliu, Coral
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2014
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493188/
https://ncbi.nlm.nih.gov/pubmed/25119316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12312
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