Triple combination immunotherapy with GVAX, anti-PD-1 monoclonal antibody, and agonist anti-OX40 monoclonal antibody is highly effective against murine intracranial glioma

Single-agent immunotherapy, including with immune checkpoint inhibition with anti-PD-1 antibody, has not extended survival in patients with malignant glioma. However, PD-1 inhibition may still play a role in combination immunotherapy with multiple agents. In this study, we evaluated anti-PD-1 antibo...

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Опубликовано в: :Oncoimmunology
Главные авторы: Jahan, Nusrat, Talat, Hammad, Alonso, Andrea, Saha, Dipongkor, Curry, William T.
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2019
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492981/
https://ncbi.nlm.nih.gov/pubmed/31069135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1577108
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