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Oncolytic viruses: how “lytic” must they be for therapeutic efficacy?

Oncolytic viruses (OVs) preferentially target and kill cancer cells without affecting healthy cells through a multi-modal mechanism of action. While historically the direct killing activity of OVs was considered the primary mode of action, initiation or augmentation of a host antitumor immune respon...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Davola, Maria Eugenia, Mossman, Karen Louise
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492965/
https://ncbi.nlm.nih.gov/pubmed/31069150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1596006
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