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Protein Kinases Alter the Allosteric Modulation of the Serotonin Transporter In Vivo and In Vitro

AIM: Studies using S‐ and R‐enantiomers of the SSRI citalopram have shown that R‐citalopram exerts an antagonistic effect on the efficacy of the antidepressant S‐citalopram (escitalopram) through an interaction at an allosteric modulator site on the serotonin transporter (SERT). Here, we show that p...

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Publicado en:CNS Neurosci Ther
Main Authors: Mnie‐Filali, Ouissame, Lau, Thorsten, Matthaeus, Friederike, Abrial, Erika, Delcourte, Sarah, El Mansari, Mostafa, Pershon, Alan, Schloss, Patrick, Sánchez, Connie, Haddjeri, Nasser
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492859/
https://ncbi.nlm.nih.gov/pubmed/27171685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12562
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