The Potential of Indole/Indolylquinoline Compounds in Tau Misfolding Reduction by Enhancement of HSPB1

BACKGROUND: Neurofibrillary tangles formed from tau misfolding have long been considered one of the pathological hallmarks of Alzheimer's disease (AD). The misfolding of tau in AD correlates with the clinical progression of AD and inhibition or reversal of tau misfolding may protect the affecte...

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Pubblicato in:CNS Neurosci Ther
Autori principali: Chang, Kuo‐Hsuan, Lin, Chih‐Hsin, Chen, Hsuan‐Chiang, Huang, Hsin‐Yu, Chen, Shu‐Ling, Lin, Te‐Hsien, Ramesh, Chintakunta, Huang, Chin‐Chang, Fung, Hon‐Chung, Wu, Yih‐Ru, Huang, Hei‐Jen, Lee‐Chen, Guey‐Jen, Hsieh‐Li, Hsiu Mei, Yao, Ching‐Fa
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492720/
https://ncbi.nlm.nih.gov/pubmed/27424519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12592
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