Adipose‐Specific Lipin‐1 Overexpression Renders Hepatic Ferroptosis and Exacerbates Alcoholic Steatohepatitis in Mice

Lipin‐1 is a Mg(2+)‐dependent phosphatidic acid phosphohydrolase involved in the generation of diacylglycerol during synthesis of phospholipids and triglycerides. Ethanol‐mediated inhibitory effects on adipose‐specific lipin‐1 expression were associated with experimental steatohepatitis in rodents....

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Bibliografische gegevens
Gepubliceerd in:Hepatol Commun
Hoofdauteurs: Zhou, Zhou, Ye, Ting Jie, Bonavita, Gregory, Daniels, Michael, Kainrad, Noah, Jogasuria, Alvin, You, Min
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492478/
https://ncbi.nlm.nih.gov/pubmed/31061954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1333
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