Safety and tolerability of donepezil 23 mg with or without intermediate dose titration in patients with Alzheimer’s disease taking donepezil 10 mg: a multicenter, randomized, open-label, parallel-design, three-arm, prospective trial

BACKGROUND: High-dose donepezil is currently prescribed for patients with Alzheimer’s disease (AD) who showed poor or waning response to a lower dose at the risk of increasing cholinergic side effects. However, the adverse events (AEs) depending on the method of dose escalation have not been clarifi...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Hong, Yun Jeong, Han, Hyun Jeong, Youn, Young Chul, Park, Kyung Won, Yang, Dong Won, Kim, SangYun, Kim, Hwa Jung, Kim, Ji Eun, Lee, Jae-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492390/
https://ncbi.nlm.nih.gov/pubmed/31039806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0492-1
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