Evidence from genome wide association studies implicates reduced control of Epstein-Barr virus infection in multiple sclerosis susceptibility

BACKGROUND: Genome wide association studies have identified > 200 susceptibility loci accounting for much of the heritability of multiple sclerosis (MS). Epstein-Barr virus (EBV), a memory B cell tropic virus, has been identified as necessary but not sufficient for development of MS. The molecula...

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Veröffentlicht in:Genome Med
Hauptverfasser: Afrasiabi, Ali, Parnell, Grant P., Fewings, Nicole, Schibeci, Stephen D., Basuki, Monica A., Chandramohan, Ramya, Zhou, Yuan, Taylor, Bruce, Brown, David A., Swaminathan, Sanjay, McKay, Fiona C., Stewart, Graeme J., Booth, David R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492329/
https://ncbi.nlm.nih.gov/pubmed/31039804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0640-z
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