Nutritionally Derived Metabolic Cues Typical of the Obese Microenvironment Increase Cholesterol Efflux Capacity of Adipose Tissue Macrophages

BACKGROUND: Cholesterol retention within plasma membranes of macrophages is associated with increased inflammatory signaling. Cholesterol efflux via the transporters ABCA1, ABCG1, and SR‐BI to high‐density lipoprotein (HDL) particles is a critical mechanism to maintain cellular cholesterol homeostas...

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Pubblicato in:Mol Nutr Food Res
Autori principali: O'Reilly, Marcella E., Kajani, Sarina, Ralston, Jessica C., Lenighan, Yvonne M., Roche, Helen M., McGillicuddy, Fiona C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492173/
https://ncbi.nlm.nih.gov/pubmed/30411491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201800713
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