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Assessing the robustness of sisVIVE in a Mendelian randomization study to estimate the causal effect of body mass index on income using multiple SNPs from understanding society

The “some invalid, some valid instrumental variable estimator” (sisVIVE) is a lasso‐based method for instrumental variables (IVs) regression of outcome on an exposure. In principle, sisVIVE is robust to some of the IVs in the analysis being invalid, in the sense of being related to the outcome varia...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Bao, Yanchun, Clarke, Paul S., Smart, Melissa, Kumari, Meena
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492086/
https://ncbi.nlm.nih.gov/pubmed/30565280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.8066
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