Patient‐Focused Drug Development Methods for Benefit–Risk Assessments: A Case Study Using a Discrete Choice Experiment for Antiepileptic Drugs

Regulatory decisions may be enhanced by incorporating patient preferences for drug benefit and harms. This study demonstrates a method of weighting clinical evidence by patients’ benefit–risk preferences. Preference weights, derived from discrete choice experiments, were applied to clinical trial da...

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Bibliografiske detaljer
Udgivet i:Clin Pharmacol Ther
Main Authors: Holmes, Emily A.F., Plumpton, Catrin, Baker, Gus A., Jacoby, Ann, Ring, Adele, Williamson, Paula, Marson, Anthony, Hughes, Dyfrig A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491963/
https://ncbi.nlm.nih.gov/pubmed/30204252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1231
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