The Analysis of Key Factors Related to ADCs Structural Design

Antibody–drug conjugates (ADCs) have developed rapidly in recent decades. However, it is complicated to map out a perfect ADC that requires optimization of multiple parameters including antigens, antibodies, linkers, payloads, and the payload-linker linkage. The therapeutic targets of the ADCs are e...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Autores principales: Tang, Haichao, Liu, Yan, Yu, Zhaojin, Sun, Mingli, Lin, Lu, Liu, Wensi, Han, Qiang, Wei, Minjie, Jin, Ying
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491742/
https://ncbi.nlm.nih.gov/pubmed/31068807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00373
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