Glucocorticoids Target Ependymal Glia and Inhibit Repair of the Injured Spinal Cord

Following injury, the mammalian spinal cord forms a glial scar and fails to regenerate. In contrast, vertebrate fish spinal cord tissue regenerates significantly to restore function. Cord transection in zebrafish (Danio rerio) initially causes paralysis and neural cell death. Subsequently, ependymal...

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Bibliographic Details
Published in:Front Cell Dev Biol
Main Authors: Nelson, Craig M., Lennon, Vanda A., Lee, Han, Krug, Randall G., Kamalova, Aichurok, Madigan, Nicolas N., Clark, Karl J., Windebank, Anthony J., Henley, John R.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Cell and Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491705/
https://ncbi.nlm.nih.gov/pubmed/31069223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00056
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