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High dose of dexamethasone protects against EAE-induced motor deficits but impairs learning/memory in C57BL/6 mice

Multiple sclerosis (MS) is an autoimmune and neuroinflammatory disease characterized by demyelination of the Central Nervous System. Immune cells activation and release of pro-inflammatory cytokines play a crucial role in the disease modulation, decisively contributing to the neurodegeneration obser...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: dos Santos, Nilton, Novaes, Leonardo S., Dragunas, Guilherme, Rodrigues, Jennifer R., Brandão, Wesley, Camarini, Rosana, Peron, Jean Pierre Schatzmann, Munhoz, Carolina Demarchi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491620/
https://ncbi.nlm.nih.gov/pubmed/31040362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43217-3
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