Development and application of a high-content virion display human GPCR array

Human G protein-coupled receptors (GPCRs) respond to various ligands and stimuli. However, GPCRs rely on membrane for proper folding, making their biochemical properties difficult to study. By displaying GPCRs in viral envelopes, we fabricated a Virion Display (VirD) array containing 315 non-olfacto...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Syu, Guan-Da, Wang, Shih-Chin, Ma, Guangzhong, Liu, Shuang, Pearce, Donna, Prakash, Atish, Henson, Brandon, Weng, Lien-Chun, Ghosh, Devlina, Ramos, Pedro, Eichinger, Daniel, Pino, Ignacio, Dong, Xinzhong, Xiao, Jie, Wang, Shaopeng, Tao, Nongjian, Kim, Kwang Sik, Desai, Prashant J., Zhu, Heng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491619/
https://ncbi.nlm.nih.gov/pubmed/31040288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09938-9
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