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Identification of eukaryotic UDP-galactopyranose mutase inhibitors using the ThermoFAD assay

Aspergillus fumigatus is a human pathogen responsible for deadly infections in immune-compromised patients. A potential strategy for treating A. fumigatus infections is by targeting the biosynthesis of cell wall components, such as galactofuranase, which is absent in humans. Galactofuranose biosynth...

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Vydáno v:Biochem Biophys Res Commun
Hlavní autoři: del Campo, Julia S. Martín, Eckshtain-Levi, Meital, Sobrado, Pablo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491354/
https://ncbi.nlm.nih.gov/pubmed/28919416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.09.074
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