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Timing of First-in-Child Trials of FDA Approved Oncology Drugs

AIM: The lag time between initial human studies of oncology agents to the first-in-child clinical trials of these agents has not been defined. METHODS: We conducted a systematic analysis of time from first-in-human trials to first-in-child trials (age of eligibility of < 18 years) of agents first...

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Veröffentlicht in:Eur J Cancer
Hauptverfasser: Neel, Dylan V., Shulman, David S., DuBois, Steven G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491224/
https://ncbi.nlm.nih.gov/pubmed/30928805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2019.02.011
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