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Prussian blue nanoparticles-based antigenicity and adjuvanticity trigger robust antitumor immune responses against neuroblastoma

We describe the synthesis of CpG oligodeoxynucleotide-coated Prussian blue nanoparticles (CpG-PBNPs) that function as a nanoimmunotherapy for neuroblastoma, a common childhood cancer. These CpG-PBNPs increase the antigenicity and adjuvanticity of treated tumors, ultimately driving robust antitumor i...

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Detalhes bibliográficos
Publicado no:Biomater Sci
Main Authors: Cano-Mejia, Juliana, Bookstaver, Michelle L., Sweeney, Elizabeth E., Jewell, Christopher M., Fernandes, Rohan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491208/
https://ncbi.nlm.nih.gov/pubmed/30789175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8bm01553h
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