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The C-terminal helix 9 motif in rat cannabinoid receptor type 1 regulates axonal trafficking and surface expression

Cannabinoid type one receptor (CB1R) is only stably surface expressed in axons, where it downregulates neurotransmitter release. How this tightly regulated axonal surface polarity is established and maintained is unclear. To address this question, we used time-resolved imaging to determine the traff...

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Библиографические подробности
Опубликовано в: :eLife
Главные авторы: Fletcher-Jones, Alexandra, Hildick, Keri L, Evans, Ashley J, Nakamura, Yasuko, Wilkinson, Kevin A, Henley, Jeremy M
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491034/
https://ncbi.nlm.nih.gov/pubmed/31036155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44252
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