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The C-terminal helix 9 motif in rat cannabinoid receptor type 1 regulates axonal trafficking and surface expression

Cannabinoid type one receptor (CB1R) is only stably surface expressed in axons, where it downregulates neurotransmitter release. How this tightly regulated axonal surface polarity is established and maintained is unclear. To address this question, we used time-resolved imaging to determine the traff...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Fletcher-Jones, Alexandra, Hildick, Keri L, Evans, Ashley J, Nakamura, Yasuko, Wilkinson, Kevin A, Henley, Jeremy M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491034/
https://ncbi.nlm.nih.gov/pubmed/31036155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44252
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