Oxidized low-density lipoprotein (oxLDL) supports Mycobacterium tuberculosis survival in macrophages by inducing lysosomal dysfunction

Type 2 diabetes mellitus (DM) is a major risk factor for developing tuberculosis (TB). TB-DM comorbidity is expected to pose a serious future health problem due to the alarming rise in global DM incidence. At present, the causal underlying mechanisms linking DM and TB remain unclear. DM is associate...

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Publicado en:PLoS Pathog
Autores principales: Vrieling, Frank, Wilson, Louis, Rensen, Patrick C. N., Walzl, Gerhard, Ottenhoff, Tom H. M., Joosten, Simone A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6490946/
https://ncbi.nlm.nih.gov/pubmed/30998773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007724
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