Effect of treatment with 5‐lipoxygenase inhibitor VIA‐2291 (atreleuton) on coronary plaque progression: a serial CT angiography study

BACKGROUND: Inflammation has a key role in the process of atherosclerosis. Production of leukotrienes by 5‐lipoxygenase has been linked to atherosclerotic plaques and cardiovascular events. HYPOTHESIS: In this study, a selective 5‐LO inhibitor will slow plaque progression using serial cardiac comput...

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Vydáno v:Clin Cardiol
Hlavní autoři: Matsumoto, Suguru, Ibrahim, Reda, Grégoire, Jean C., L'Allier, Philippe L., Pressacco, Josephine, Tardif, Jean‐Claude, Budoff, Matthew J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Periodicals, Inc 2016
Témata:
Clinical Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6490367/
https://ncbi.nlm.nih.gov/pubmed/27883201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/clc.22646
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