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Rasagiline delays retinal degeneration in a mouse model of retinitis pigmentosa via modulation of Bax/Bcl‐2 expression

AIMS: Retinitis pigmentosa (RP) is an inherited disease characterized by a progressive degeneration of rod photoreceptors. An imbalance between pro‐ and antiapoptotic factors, such as Bax/Bcl‐2, has been involved in retinal degeneration. To date, no cure or effective treatments are available for RP....

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Dettagli Bibliografici
Pubblicato in:CNS Neurosci Ther
Autori principali: Garcia‐Delgado, Ana B., Valdés‐Sánchez, Lourdes, Calado, Sofia M., Diaz‐Corrales, Francisco J., Bhattacharya, Shom S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489995/
https://ncbi.nlm.nih.gov/pubmed/29372592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12805
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