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Cholinesterase targeting by polyphenols: A therapeutic approach for the treatment of Alzheimer’s disease

Alzheimer’s disease (AD) is a progressive irreversible neurodegenerative disorder characterized by excessive deposition of β‐amyloid (Aβ) oligomers, and neurofibrillary tangles (NFTs), comprising of hyperphosphorylated tau proteins. The cholinergic system has been suggested as the earliest and most...

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Bibliographic Details
Published in:CNS Neurosci Ther
Main Authors: Jabir, Nasimudeen R., Khan, Fayaz Rahman, Tabrez, Shams
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489761/
https://ncbi.nlm.nih.gov/pubmed/29770579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12971
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