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Biochemical characterization of recombinant Avihepatovirus 3C protease and its localization

BACKGROUND: The picornaviral 3C protease mediates viral polyprotein maturation and multiple cleavages of host proteins to modulate viral translation and transcription. The 3C protease has been regarded as a valid target due to its structural similarity among different picornaviruses and minimal sequ...

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Detalhes bibliográficos
Publicado no:Virol J
Main Authors: Sun, Di, Wang, Mingshu, Wen, Xingjian, Mao, Sai, Cheng, Anchun, Jia, Renyong, Yang, Qiao, Wu, Ying, Zhu, Dekang, Chen, Shun, Liu, Mafeng, Zhao, Xinxin, Zhang, Shaqiu, Chen, Xiaoyue, Liu, Yunya, Yu, Yanling, Zhang, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489322/
https://ncbi.nlm.nih.gov/pubmed/31036013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-019-1155-3
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