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pwrEWAS: a user-friendly tool for comprehensive power estimation for epigenome wide association studies (EWAS)

BACKGROUND: When designing an epigenome-wide association study (EWAS) to investigate the relationship between DNA methylation (DNAm) and some exposure(s) or phenotype(s), it is critically important to assess the sample size needed to detect a hypothesized difference with adequate statistical power....

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Détails bibliographiques
Publié dans:BMC Bioinformatics
Auteurs principaux: Graw, Stefan, Henn, Rosalyn, Thompson, Jeffrey A., Koestler, Devin C.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489300/
https://ncbi.nlm.nih.gov/pubmed/31035919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2804-7
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