The opposing effects of interferon-beta and oncostatin-M as regulators of cancer stem cell plasticity in triple-negative breast cancer

BACKGROUND: Highly aggressive, metastatic and therapeutically resistant triple-negative breast cancers (TNBCs) are often enriched for cancer stem cells (CSC). Cytokines within the breast tumor microenvironment (TME) influence the CSC state by regulating tumor cell differentiation programs. Two preva...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Doherty, Mary R., Parvani, Jenny G., Tamagno, Ilaria, Junk, Damian J., Bryson, Benjamin L., Cheon, Hyeon Joo, Stark, George R., Jackson, Mark W.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489282/
https://ncbi.nlm.nih.gov/pubmed/31036052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-019-1136-x
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