Effect of Celastrus orbiculatus in inhibiting Helicobacter pylori induced inflammatory response by regulating epithelial mesenchymal transition and targeting miR-21/PDCD4 signaling pathway in gastric epithelial cells

BACKGROUND: The extract of Celastrus orbiculatus (COE) have been studied for anti-Helicobacter pylori (H. pylori) activity and anti-cancer effects in vitro and in vivo. However, the molecular mechanism by which COE inhibits H. pylori-induced inflammatory response has not been fully elucidated so far...

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Detalhes bibliográficos
Publicado no:BMC Complement Altern Med
Main Authors: Zhu, Yaodong, Liu, Lei, Hu, Lei, Dong, Wenqing, Zhang, Mei, Liu, Yanqing, Li, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489279/
https://ncbi.nlm.nih.gov/pubmed/31035975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-019-2504-x
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