Clinico-pathological associations and concomitant mutations of the RAS/RAF pathway in metastatic colorectal cancer

BACKGROUND: Over the past few years, next-generation sequencing (NGS) has become reliable and cost-effective, and its use in clinical practice has become a reality. A relevant role for NGS is the prediction of response to anti-EGFR agents in metastatic colorectal cancer (mCRC), where multiple exons...

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Bibliografiske detaljer
Udgivet i:J Transl Med
Main Authors: Isnaldi, Edoardo, Garuti, Anna, Cirmena, Gabriella, Scabini, Stefano, Rimini, Edoardo, Ferrando, Lorenzo, Lia, Michela, Murialdo, Roberto, Tixi, Lucia, Carminati, Enrico, Panaro, Andrea, Gallo, Maurizio, Grillo, Federica, Mastracci, Luca, Repetto, Lazzaro, Fiocca, Roberto, Romairone, Emanuele, Zoppoli, Gabriele, Ballestrero, Alberto
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489172/
https://ncbi.nlm.nih.gov/pubmed/31036005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1879-2
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