Abnormal expression and mutation of the RBPJ gene may be involved in CD59(−) clonal proliferation in paroxysmal nocturnal hemoglobinuria

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal proliferative disease of hematopoietic stem cells. Various gene mutations, including the phosphatidylinositol glycan anchor biosynthesis class A (PIG-A) gene, may contribute to the proliferation of PNH clones. In order to explore the me...

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Veröffentlicht in:Exp Ther Med
Hauptverfasser: Li, Liyan, Liu, Hui, Wang, Honglei, Liu, Zhaoyun, Chen, Yingying, Li, Lijuan, Song, Jia, Wang, Guojin, Fu, Rong
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2019
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489004/
https://ncbi.nlm.nih.gov/pubmed/31086586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7475
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