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Blockade of TREM-1 prevents vitreoretinal neovascularization in mice with oxygen-induced retinopathy

In pathological retinal neovascularization (RNV) disorders, the retina is infiltrated by activated leukocytes and macrophages. Triggering receptor expressed on myeloid cells 1 (TREM-1), an inflammation amplifier, activates monocytes and macrophages and plays an important role in cancer, autoimmune a...

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Bibliografiske detaljer
Udgivet i:Biochim Biophys Acta Mol Basis Dis
Main Authors: Rojas, Modesto A., Shen, Zu T., Caldwell, Ruth B., Sigalov, Alexander B.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488934/
https://ncbi.nlm.nih.gov/pubmed/29730341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2018.05.001
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