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Amyloid beta soluble forms and plasminogen activation system in Alzheimer’s disease: Consequences on extracellular maturation of brain‐derived neurotrophic factor and therapeutic implications

Soluble oligomeric forms of amyloid beta (Aβ) play an important role in causing the cognitive deficits in Alzheimer’s disease (AD) by targeting and disrupting synaptic pathways. Thus, the present research is directed toward identifying the neuronal pathways targeted by soluble forms and, accordingly...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:CNS Neurosci Ther
Main Authors: Angelucci, Francesco, Čechová, Kateřina, Průša, Richard, Hort, Jakub
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488905/
https://ncbi.nlm.nih.gov/pubmed/30403004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13082
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