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Amyloid beta soluble forms and plasminogen activation system in Alzheimer’s disease: Consequences on extracellular maturation of brain‐derived neurotrophic factor and therapeutic implications

Soluble oligomeric forms of amyloid beta (Aβ) play an important role in causing the cognitive deficits in Alzheimer’s disease (AD) by targeting and disrupting synaptic pathways. Thus, the present research is directed toward identifying the neuronal pathways targeted by soluble forms and, accordingly...

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Publicat a:CNS Neurosci Ther
Autors principals: Angelucci, Francesco, Čechová, Kateřina, Průša, Richard, Hort, Jakub
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488905/
https://ncbi.nlm.nih.gov/pubmed/30403004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13082
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