Macrolide derivatives reduce proinflammatory macrophage activation and macrophage‐mediated neurotoxicity

INTRODUCTION: Azithromycin (AZM) and other macrolide antibiotics are applied as immunomodulatory treatments for CNS disorders. The immunomodulatory and antibiotic properties of AZM are purportedly independent. AIMS: To improve the efficacy and reduce antibiotic resistance risk of AZM‐based therapies...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Zhang, Bei, Kopper, Timothy J., Liu, Xiaodong, Cui, Zheng, Van Lanen, Steven G., Gensel, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488883/
https://ncbi.nlm.nih.gov/pubmed/30677254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13092
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