Epigenetically Down-Regulated Acetyltransferase PCAF Increases the Resistance of Colorectal Cancer to 5-Fluorouracil()

Only 10%–20% of colorectal cancer (CRC) patients observe effective responses to 5-fluorouracil (5-FU) based chemo-treatment. We used real-time PCR array and Western blot analysis to examine the expression alteration of acetyltransferases and deacetylases in 5-FU resistant CRC cell lines as compared...

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Опубликовано в: :Neoplasia
Главные авторы: Liu, Tong, Wang, Xiang, Hu, Wenquan, Fang, Zhi, Jin, Ying, Fang, Xuedong, Miao, Qing Robert
Формат: Artigo
Язык:Inglês
Опубликовано: Neoplasia Press 2019
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Original article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488821/
https://ncbi.nlm.nih.gov/pubmed/31042625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.03.011
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