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Elamipretide Improves Mitochondrial Function in the Failing Human Heart
Negative alterations of mitochondria are known to occur in heart failure (HF). This study investigated the novel mitochondrial-targeted therapeutic agent elamipretide on mitochondrial and supercomplex function in failing human hearts ex vivo. Freshly explanted failing and nonfailing ventricular tiss...
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| Publicado no: | JACC Basic Transl Sci |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6488757/ https://ncbi.nlm.nih.gov/pubmed/31061916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.12.005 |
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