LncRNA EPR controls epithelial proliferation by coordinating Cdkn1a transcription and mRNA decay response to TGF-β

Long noncoding RNAs (lncRNAs) are emerging as regulators of fundamental biological processes. Here we report on the characterization of an intergenic lncRNA expressed in epithelial tissues which we termed EPR (Epithelial cell Program Regulator). EPR is rapidly downregulated by TGF-β and its sustaine...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Rossi, Martina, Bucci, Gabriele, Rizzotto, Dario, Bordo, Domenico, Marzi, Matteo J., Puppo, Margherita, Flinois, Arielle, Spadaro, Domenica, Citi, Sandra, Emionite, Laura, Cilli, Michele, Nicassio, Francesco, Inga, Alberto, Briata, Paola, Gherzi, Roberto
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488594/
https://ncbi.nlm.nih.gov/pubmed/31036808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09754-1
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