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The characterization of Thermotoga maritima Arginine Binding Protein variants demonstrates that minimal local strains have an important impact on protein stability

The Ramachandran plot is a versatile and valuable tool that provides fundamental information for protein structure determination, prediction, and validation. The structural/thermodynamic effects produced by forcing a residue to adopt a conformation predicted to be forbidden were here explored using...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Balasco, Nicole, Smaldone, Giovanni, Vigorita, Marilisa, Del Vecchio, Pompea, Graziano, Giuseppe, Ruggiero, Alessia, Vitagliano, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488590/
https://ncbi.nlm.nih.gov/pubmed/31036855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43157-y
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