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Developmental Regulation of the Gut-Liver (FGF19-CYP7A1) Axis in Neonates

INTRODUCTION: Fibroblast growth factor 19 (FGF19) is a gut-derived hormone that regulates the expression of CYP7A1, the rate-limiting enzyme in bile acid (BA) synthesis pathway. Dysregulation of the FGF19-CYP7A1 (gut-liver) axis is associated with cholestatic liver disease. Infants, especially prete...

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Detalhes bibliográficos
Publicado no:J Matern Fetal Neonatal Med
Main Authors: Memon, Naureen, Griffin, Ian J, Lee, Chris W, Herdt, Aimee, Weinberger, Barry I, Hegyi, Thomas, Carayannopoulos, Mary O, Aleksunes, Lauren M, Guo, Grace L
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488437/
https://ncbi.nlm.nih.gov/pubmed/30122083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14767058.2018.1513483
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