Concomitant TP53 mutations with response to crizotinib treatment in patients with ALK‐rearranged non‐small‐cell lung cancer

BACKGROUND: TP53 mutations are the most prevalent mutations detected in non‐small‐cell lung cancer (NSCLC) and have been revealed as a negative prognostic biomarker of outcome. The impact of concomitant TP53 mutations in ALK‐rearranged NSCLC remains uncertain. METHODS: Tumor samples from 64 ALK‐rear...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Med
Hauptverfasser: Song, Peng, Zhang, Fanshuang, Li, Yan, Yang, Guangjian, Li, Wenbin, Ying, Jianming, Gao, Shugeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Clinical Cancer Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488212/
https://ncbi.nlm.nih.gov/pubmed/30843662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2043
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