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Global brain ischemia in rats is associated with mitochondrial release and downregulation of Mfn2 in the cerebral cortex, but not the hippocampus

Mitochondria are crucial for neuronal cell survival and death through their functions in ATP production and the intrinsic pathway of apoptosis. Mitochondrial dysfunction is considered to play a central role in several serious human diseases, including neurodegenerative diseases, such as Parkinson�...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Med
Hauptverfasser: Klacanova, Katarina, Kovalska, Maria, Chomova, Maria, Pilchova, Ivana, Tatarkova, Zuzana, Kaplan, Peter, Racay, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488171/
https://ncbi.nlm.nih.gov/pubmed/31017259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2019.4168
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