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Human collectin-11 (COLEC11) and its synergic genetic interaction with MASP2 are associated with the pathophysiology of Chagas Disease

Chagas Disease (CD) is an anthropozoonosis caused by Trypanosoma cruzi. With complex pathophysiology and variable clinical presentation, CD outcome can be influenced by parasite persistence and the host immune response. Complement activation is one of the primary defense mechanisms against pathogens...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Sandri, Thaisa Lucas, Andrade, Fabiana Antunes, Lidani, Kárita Cláudia Freitas, Einig, Elias, Boldt, Angelica Beate Winter, Mordmüller, Benjamin, Esen, Meral, Messias-Reason, Iara J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488100/
https://ncbi.nlm.nih.gov/pubmed/30995222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007324
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