Treatment-Related Adverse Events of PD-1 and PD-L1 Inhibitors in Clinical Trials: A Systematic Review and Meta-analysis

IMPORTANCE: Programmed cell death (PD-1) and programmed cell death ligand 1 (PD-L1) inhibitors have been increasingly used in cancer therapy. Understanding the treatment-related adverse events of these drugs is critical for clinical practice. OBJECTIVE: To evaluate the incidences of treatment-relate...

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Опубликовано в: :JAMA Oncol
Главные авторы: Wang, Yucai, Zhou, Shouhao, Yang, Fang, Qi, Xinyue, Wang, Xin, Guan, Xiaoxiang, Shen, Chan, Duma, Narjust, Vera Aguilera, Jesus, Chintakuntlawar, Ashish, Price, Katharine A., Molina, Julian R., Pagliaro, Lance C., Halfdanarson, Thorvardur R., Grothey, Axel, Markovic, Svetomir N., Nowakowski, Grzegorz S., Ansell, Stephen M., Wang, Michael L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Medical Association 2019
Предметы:
Original Investigation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487913/
https://ncbi.nlm.nih.gov/pubmed/31021376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2019.0393
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