Association of Checkpoint Inhibitor–Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non–Small Cell Lung Cancer

IMPORTANCE: Immunotherapy with checkpoint inhibitors targeting the PD-1 (programmed cell death 1) axis has brought notable progress in patients with non–small cell lung cancer (NSCLC) and other cancers. However, autoimmune toxic effects are frequent and poorly understood, making it important to unde...

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Vydáno v:JAMA Oncol
Hlavní autoři: Berner, Fiamma, Bomze, David, Diem, Stefan, Ali, Omar Hasan, Fässler, Mirjam, Ring, Sandra, Niederer, Rebekka, Ackermann, Christoph J., Baumgaertner, Petra, Pikor, Natalia, Cruz, Cristina Gil, van de Veen, Willem, Akdis, Mübeccel, Nikolaev, Sergey, Läubli, Heinz, Zippelius, Alfred, Hartmann, Fabienne, Cheng, Hung-Wei, Hönger, Gideon, Recher, Mike, Goldman, Jonathan, Cozzio, Antonio, Früh, Martin, Neefjes, Jacques, Driessen, Christoph, Ludewig, Burkhard, Hegazy, Ahmed N., Jochum, Wolfram, Speiser, Daniel E., Flatz, Lukas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2019
Témata:
Brief Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487908/
https://ncbi.nlm.nih.gov/pubmed/31021392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2019.0402
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