FAM175B promotes apoptosis by inhibiting ATF4 ubiquitination in esophageal squamous cell carcinoma

FAM175B is a reported regulator of p53 and suppresses tumorigenesis in numerous types of cancer, but very little is known about its function in esophageal squamous cell carcinomas (ESCCs), almost 70% of which exhibit mutations in p53. Here, we report that FAM175B expression is downregulated in high‐...

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Veröffentlicht in:Mol Oncol
Hauptverfasser: Zhao, Yu, Yu, Yang, Li, Hengcun, Zhang, Zheng, Guo, Shuilong, Zhu, Shengtao, Guo, Qingdong, Li, Peng, Min, Li, Zhang, Shutian
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487841/
https://ncbi.nlm.nih.gov/pubmed/30854784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12474
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